Significance of apoptotic cell death in systemic complications with severe acute pancreatitis

Alcohol abuse-related severe acute pancreatitis with rhabdomyolysis complications

Non-traumatic rhabdomyolysis is a rare complication of acute pancreatitis. One of the major risk factors of both acute pancreatitis and rhabdomyolysis is alcohol abuse. However, only a few studies have reported the prognosis and association of severe acute pancreatitis (SAP) and rhabdomyolysis in alcohol abuse patients. In the present study, we report two cases presenting with SAP complicated b...

Complications of Acute Pancreatitis

IntroductIon Acute pancreatitis is an acute inflammatory process of the pancreas, which has variable involvement of other regional tissues and/or remote organ systems. The disease can be classified as mild or severe depending on the extent of inflammation and organ involvement. Mild pancreatitis consists of interstitial (edematous) pancreatitis on imaging with minimal or no extrapancreatic orga...

Analysis of factors related to death of severe acute pancreatitis

The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis

Background: Tim-3 has been considered as an ideal target for the immunotherapy of inflammation, but it is unclear whether Tim-3 also plays an important role in acute pancreatitis (AP), as well. Objective: To identify the immunomodulatory effects and mechanisms of Tim-3 action in the early stages of severe acute pancreatitis in mice. Methods: Ma...

Lung complications in acute pancreatitis.

CONTEXT Severe acute pancreatitis has long been known to be a cause of pulmonary dysfunction and multisystem organ failure. OBJECTIVE We evaluated the spectrum of pulmonary dysfunction in acute pancreatitis. METHODS Over a period of one year, 60 patients referred to us with a diagnosis of acute pancreatitis on the basis of clinical findings, CT and elevated serum amylase level were studied ...